Bone/Mineral Metabolism News

Osteoporosis therapies work equally well for women at high risk for fracture with high or low bone mineral density, according to data from the virtual American Society for Bone and Mineral Research Annual Meeting.

Palovarotene reduced new heterotopic ossification volume in children and adults with fibrodysplasia ossificans progressiva, according to data from a phase 3 trial.

Treatment with the monoclonal antibody burosumab led to normalized serum phosphorus levels and improvements in rickets severity and lower-limb deformity among young children with X-linked hypophosphatemia, according to a speaker.

A single dose of zoledronic acid effectively maintains large and rapid gains in spine and hip bone mineral density after 15 months of overlapping teriparatide and denosumab therapy, according to a speaker.

Youths with type 1 diabetes have weaker bone and lower muscle strength than their healthy peers, according to a presenter at the American Society for Bone and Mineral Research virtual meeting.

Women who sustain any type of osteoporotic fracture have higher adjusted all-cause health care costs and indirect costs in the 5 years after fracture compared with matched nonfracture controls, according to a speaker.

Adults with osteoporosis prescribed zoledronic acid have an increased risk for atrial fibrillation when compared with denosumab, according to a study data.

There is minimal difference among bioavailable, free and total serum 25-hydroxyvitamin D for predicting bone health in older adults, according to data presented at the American Society for Bone and Mineral Research virtual meeting.

Sleep-wake circadian rhythm is an important mechanism to maintain biological timekeeping, and disruptions from light exposure, dietary challenges and timing of food intake can have cardiometabolic consequences, according to a speaker.

Compared with healthy peers, a cohort of children and teens with type 1 diabetes accrued less bone over 12 months, particularly those with high urinary calcium excretion, making them more susceptible to fractures, according to study data.