Bone/Mineral Metabolism News

Postmenopausal women with type 2 diabetes have increased bone mineral content and lower bone turnover markers vs. those with normal or impaired glucose tolerance, according to data published in the Journal of Bone and Mineral Research.

Among older adults with an elevated fall risk and low serum 25-dydroxyvitamin D levels, daily vitamin D3 supplementation at doses of 1,000 IU did not prevent falls compared with a 200 IU dose, according to a randomized clinical trial.

Among patients using long-term glucocorticoids, denosumab is superior to alendronate in increasing bone mineral density in the spine after 1 year, according to a speaker at ACR Convergence 2020.

Romosozumab as a first treatment produces ‘substantial gains’ in hip and lumbar spine bone mineral density within 1 year, a result that is augmented by then transitioning to a potent antiresorptive, according to a study.

Patients with heart failure and reduced ejection fraction who were randomized to dapagliflozin had half the risk of moderate to severe hyperkalemia vs. placebo, according to results of the DAPA-HF trial presented at ASN Kidney Week.

Morphometric vertebral fractures are one of the most common comorbidities among adults hospitalized with COVID-19, and the presence of such fractures may predict the severity of disease outcomes, study data show.

Participants in the UK Biobank who had a higher bone speed of sound were more likely to have good cardiovascular health, according to a study published in The Journal of Bone and Mineral Research.

Older adults without obesity, but with a high body fat percentage, have greater risks for sarcopenia and osteoporosis when compared with individuals with obesity, according to findings published in Obesity.

Increased genetic risk for Graves’ disease, autoimmune thyroiditis or hyperthyroidism is not associated with low bone mineral density or fracture risk, according to an analysis of UK Biobank data.

Women with osteoporosis are not being identified and treated at sufficient rates, according to a presenter at the 2020 Congress of Clinical Rheumatology-West.