Top endocrine news of 2022: Anti-obesity therapies, time-restricted eating and more
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The Healio and Endocrine Today Editors have compiled a list of the top endocrinology news stories from 2022.
Readers were most interested in new data released on anti-obesity medications, the impact of time-restricted eating on cardiometabolic health, a projected increase in hip fractures over the coming years, and more.
Here are 10 of Healio’s most-read endocrine news stories from 2022.
‘Mind-blowing’ weight loss with semaglutide extends to adolescents with obesity
Data from the STEP Teens phase 3a trial presented at ObesityWeek 2022 showed that once-weekly semaglutide 2.4 mg (Wegovy, Novo Nordisk) plus lifestyle intervention was associated with a 16.1% reduction in BMI at 68 weeks in a cohort of adolescents with obesity.
SURMOUNT-1: Adults achieve weight loss of 16% or more at 72 weeks with tirzepatide
In top-line results from the SURMOUNT-1 phase 3 trial, most adults with overweight or obesity achieved a mean weight loss of 16% or more at 72 weeks with 5 mg, 10 mg or 15 mg of once-weekly tirzepatide (Mounjaro, Eli Lilly).
Time-restricted eating improves cardiometabolic markers among most adults
A systematic review and meta-analysis published in The Journal of Clinical Endocrinology & Metabolism found time-restricted eating was associated with numerous cardiometabolic benefits for adults, including decreases in body weight, fat mass and fasting blood glucose.
What traditional Indian medicine teaches about eating well with diabetes
In a Diabetes in Real Life column published in August, Susan Weiner, MS, RDN, CDCES, FADCES, spoke with Parul Kharod, MS, RD, LDN, about the traditional Indian medical knowledge system known as Ayurveda and what it can reveal for people living with diabetes.
Higher body fat percentage confers higher mortality risk
In findings published in the International Journal of Obesity, researchers found having more body fat, whether determined by percentage, fat mass, fat mass index or visceral adipose tissue, was associated with a higher risk for mortality.
FDA approves teplizumab to delay type 1 diabetes onset
In November, the FDA approved teplizumab (teplizumab-mzwv, Provention Bio), a humanized anti-CD3 monoclonal antibody, to delay the onset of type 1 diabetes for adults and children aged 8 years and older with stage 2 type 1 diabetes.
Number of hip fractures projected to nearly double worldwide by 2050
Findings presented at the American Society for Bone and Mineral Research Annual Meeting in September revealed that the number of hip fractures is projected to nearly double across the globe between 2018 and 2050 as the aging population is expected to increase.
Endocrine Society condemns Texas directive defining gender-affirming care as child abuse
After a directive issued by Texas Gov. Greg Abbott in February defined gender-affirming care for adolescents as “child abuse,” The Endocrine Society released a statement condemning the directive, stating that it reflected “widespread misinformation about gender-affirming care.”
Eating potatoes in morning vegetables in evening lowers mortality risk in diabetes
In a study published in The Journal of Clinical Endocrinology & Metabolism, adults with diabetes who consumed potatoes in the morning, whole grains in the afternoon and greens and milk in the evening had a lower risk for cardiovascular events and all-cause mortality.
Time-restricted eating plus high-intensity exercise lower visceral fat for women
Women who partake in a time-restricted eating pattern and perform high-intensity interval training lose more visceral fat area than women who perform only one of the two interventions, according to findings published in Cell Metabolism.
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