May 10, 2019
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Top takeaways from AACE 2019

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Endocrine Today has compiled a list of the top five news stories posted from the American Association of Clinical Endocrinologists Scientific & Clinical Congress, held April 24-28, 2019, in Los Angeles.

Healio.com/Endocrinology readers were interested in endocrine-disrupting chemicals, role of fat loss in diabetes remission, the value of vitamin D supplements for bone health, the “weekend effect” on diabetic ketoacidosis and much more.

Supplements, cancer therapies, endocrine-disrupting chemicals can alter thyroid function

Medications, supplements, excessive iodine intake and other exogenous substances, including endocrine-disrupting chemicals, can influence multiple thyroid effects that clinicians should recognize.

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Key to type 2 diabetes remission may be loss of half a gram of pancreas fat

Adults with type 2 diabetes may be able to achieve sustainable remission from the disease by losing weight and decreasing fat in the pancreas and liver.

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Beyond calcium, vitamin D, supplements may do more harm than good for bones

When it comes to optimal bone health and fracture prevention, there is scant evidence for recommending supplementation with vitamins and minerals other than calcium and vitamin D.

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In-hospital diabetic ketoacidosis mortality risk higher on the weekend

Seeking hospital care for diabetic ketoacidosis during the weekend as opposed to during the week may increase mortality risk.

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Higher HbA1c, daily insulin injections increase diabetic ketoacidosis risk

Adults with type 1 diabetes and HbA1c levels of at least 9% are more likely to develop diabetic ketoacidosis, or DKA, than those who reach lower targets.

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New discoveries offer possible Cushing’s disease cure

More than a century has passed since the neurosurgeon and pathologist Harvey Cushing first discovered the disease that would eventually bear his name, but only recently have several key discoveries offered patients with the condition real hope for a cure.

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Antimalarial drug effective alternative to canagliflozin in type 2 diabetes

Adults with type 2 diabetes inadequately controlled with a DPP-IV inhibitor plus metformin therapy experienced an improvement in glycemic control with the antimalarial drug hydroxychloroquine that was similar to the SGLT2 inhibitor canagliflozin.

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Endocrine diseases ‘emerging epidemic’ after immune checkpoint inhibitor therapies

Recently approved immune checkpoint inhibitor therapies are now increasingly used for a variety of cancers and other conditions, yet clinicians are only beginning to confront a range of endocrinopathies triggered by such treatments, including thyroid disease, pituitary disorders and insulin-dependent diabetes.

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Controlling your online reputation requires minimal time, effort

Social media is a powerful tool that connects physicians with patients and other providers and offers a space for important conversations about health care reform and education. But even those who want nothing to do with social media cannot ignore it completely, Kevin Pho, MD, founder of the blog KevinMD.com.

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New agent reduces eye bulging in Graves’ orbitopathy, offering new hope for patients

An experimental human monoclonal antibody dramatically reduced the most debilitating symptoms of Graves’ orbitopathy, including proptosis and double vision, giving new hope to patients that a treatment for thyroid eye disease may finally be within reach.

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