April 07, 2019
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Top takeaways from ENDO 2019

Endocrine Today has compiled a list of the top five news stories posted from the Endocrine Society Annual Meeting, held March 23–26 in New Orleans.

Healio.com/Endocrinology readers were interested in meal-timing for weight loss, new diabetes guidelines for older adults, a contraceptive pill for men, and much more.

Verified meal, sleep window research explores meal timing as weight-loss strategy

Eating later into the evening was associated with going to bed later and with having a greater BMI and fat mass in a group of mostly women with overweight and obesity.

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New guideline emphasizes simpler diabetes regimens, looser glycemic targets for older adults

Treatment of diabetes in older adults remains a challenge, and a new guideline from the Endocrine Society recommends simplified medication regimens and looser glycemic targets to improve adherence and prevent treatment-related complications in this patient population.

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PIONEER 3: Oral semaglutide bests sitagliptin for HbA1c reduction

Oral semaglutide, as an add-on to metformin with or without a sulfonylurea, resulted in greater HbA1c reductions after 26 weeks compared with sitagliptin.

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CGM shows hypoglycemia common in older adults with type 1 diabetes

Older adults with type 1 diabetes spent more than an hour per day on average with blood glucose levels in the hypoglycemic range and more than 20 minutes per day with levels less than 54 mg/dL.

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Technology snags may limit adoption of current hybrid closed-loop insulin delivery system

Nearly one-third of participants in a study of first-time users of an “artificial pancreas” stopped using the system within a few months, primarily because of difficulties with the technology.

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Genomics discoveries reveal clues to preventing, treating endocrine diseases

The science of genomics is a driver for nearly everything researchers are learning about health and disease, and the pace of new discoveries is rapidly changing what is known about metabolic conditions like type 2 diabetes, according to NIH director Francis S. Collins, MD, PhD.

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Men's birth control pill shows promise in monthlong study

Healthy men assigned to a daily oral modified testosterone pill for 1 month experienced a decrease in serum testosterone consistent with effective contraception while maintaining androgenic traits such as sexual function.

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Transgender men prescribed testosterone therapy may have preserved ovarian function

At least 1 year of testosterone therapy did not reduce anti-Müllerian hormone levels or antral follicular count in a cohort of transgender men in Israel, providing evidence for preserved ovarian reserve.

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VIDEO: Exciting diabetes research unveiled at ENDO 2019

Dawn Belt Davis, MD, PhD, associate professor in the division of endocrinology, diabetes and metabolism at the University of Wisconsin School of Medicine and Public Health in Madison recaps some of the exciting diabetes research presented at this year’s Endocrine Society Annual Meeting.

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Cushing’s syndrome expert a standout in clinical practice

James Findling, MD, received the Outstanding Clinical Practitioner Award at ENDO 2019 in New Orleans. Endocrine Today spoke with Findling about his serendipitous entrance into endocrinology, his own experience with medical history and his dream of playing golf with Barack Obama.

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