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Top 5 recent obesity and weight loss news reports
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Endocrine Today has compiled a list of the top five reports about obesity and weight loss posted in the past month.
Healio.com/Endocrinology readers were interested in cause and effects of weight regain, benefits of bariatric surgery on diabetes and hypogonadism, an “obesity genotype” and more.
Metabolic changes make weight loss maintenance difficult, but not impossible
As weight decreases, unavoidable physiologic changes lead the body to defend a higher weight by ratcheting up appetite and expending less energy. This process serves to keep weight relatively stable or at a small upward trajectory throughout adult life in people with normal BMI but often prevents those with obesity from reducing to a normal weight. Read more.
After bariatric surgery, first-year weight loss may be key to improved, long-term glycemic control
In adults with obesity and type 2 diabetes who underwent bariatric surgery, acute, first-year weight loss was associated with improved HbA1c at 5 years even if the patient experienced weight regain during follow-up, according to a post hoc analysis of the STAMPEDE trial. Read more.
In severe obesity, bariatric surgery induces rapid reversal of hypogonadism
Men with severe obesity and hypogonadism who underwent sleeve gastrectomy experienced a marked increase in testosterone and prostate-specific antigen and a reduction in serum estradiol during the 1 month following the procedure. Read more.
FDA issues alert after deaths associated with intragastric balloons
The FDA issued an alert for health care providers following five additional deaths in patients with two liquid-filled intragastric balloon systems used to treat obesity, according to a press release from the agency. Read more.
Targeting ‘obesity genotype’ will require larger studies, effect sizes
Obesity is a multifactorial disease that involves a complex interplay among genetics, environment and personal habits. The genetic component is estimated to be about 40% to 50%. However, these percentages do not represent an individual’s personal risk for obesity. Read more.