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Adverse psychosocial profile common in women with diabetes, acute coronary syndrome
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Women with diabetes and incident acute coronary syndrome are more likely to report depression and anxiety compared with women without diabetes and men with diabetes, according to findings published in Diabetic Medicine.
Tricia Peters, MD, PhD, FRCPC, of the Adult Endocrinology and Training Program at McGill University in Montreal, and colleagues evaluated data from the GENESIS-PRAXY cohort study on premature acute coronary syndrome on 287 women (14.3% with type 2 diabetes) and 652 men (10.4% with type 2 diabetes) to determine whether behavioral and psychosocial factors contribute to disparities in risk and outcomes.
Compared with participants without diabetes, participants with diabetes were more likely to be obese (P < .001) and have greater waist to hip ratio. There was a trend toward more insulin use in women with diabetes compared with men with diabetes (19.5% vs. 7.35%; P = .06).
Moderate to strenuous physical activity was reported by more women with diabetes compared with men with diabetes (65.9% vs. 45.6%; P = .04). Being the primary earner was reported by more women with diabetes compared with women without diabetes (63.4% vs. 41.9%; P = .01).
Participants with diabetes were more likely to have depression compared with participants without diabetes (women, P = .03; men, P < .001). Anxiety was more likely to be reported by women with diabetes compared with women without diabetes (P = .08) and men with diabetes (P = .06). Lower levels of perceived physical health were reported by women with diabetes compared with men with diabetes (P = .03).
The risk for presenting with premature acute coronary syndrome was higher among women with diabetes compared with men without diabetes (OR = 1.4; 95% CI, 0.83-2.36).
“Awareness of disparities in behavioral and psychosocial factors among women with diabetes that may influence cardiovascular risk and outcomes could lead to targeted preventive measures to reduce morbidity and mortality,” Peters told Endocrine Today. “Moreover, clinicians may need to assess CV risk differently for women than for men, as traditional risk factors may not capture the full risk potential for this patient population. As this was a small cross-sectional study, larger prospective studies that evaluate differences in CV disease risk and outcomes for men and women with and without diabetes according to behavioral and psychosocial factors will be important to better understand the impact of sex and diabetes on CV health and to address health disparities.” – by Amber Cox
For more information:
Tricia Peters, MD, PhD, FRCPC, can be reached at tricia.peters@mail.mcgill.ca.
Disclosure: The authors report no relevant financial disclosures.
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