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Chinese adults with type 2 diabetes show decrease in CV-renal complications, death
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During a 13-year period, the incidence of cardiovascular-renal complications and death decreased in Chinese adults with type 2 diabetes living in Hong Kong, according to findings published in Diabetes Care.
Andrea O.Y. Luk, MD, MBChB, associate professor in the department of medicine and therapeutics, Prince of Wales Hospital in Hong Kong, and colleagues evaluated data from the Hong Kong Diabetes Database on 338,908 Chinese adults with type 2 diabetes to determine changes in risk factor control and incidence of complications from diabetes and death. Participants were followed from 2000 to 2012 for acute myocardial infarction, stroke, end-stage renal disease and death.
Overall, 28,360 participants died; acute MI occurred in 5,381, stroke in 11,050 and ESRD in 3,057 who had not experienced the events at baseline. A relationship was found between enrolled year and disease duration for incident stroke (P = .011) and ESRD (P < .001).
The number of participants who achieved HbA1c less than 7% increased from 32.9% in 2000-2003 to 50% in 2010-2012; the number who achieved blood pressure 130/80 mm Hg or less increased from 24.7% to 30.7% and LDL cholesterol less than 2.6 mmol/L increased from 25.8% to 38.1%.
“We found reductions in incidence of major [CV] events, renal events and all-cause death over the past decade. These trends were supported by parallel improvements in the control of modifiable risk factors and increases in uptake of pharmacological treatments of these conditions,” the researchers wrote. Notwithstanding, there remain considerable gaps in the care of patients with diabetes, and up to 50% to 70% of our patients were not achieving goals. Insofar as risks of discrete complications have fallen, given the continuous rise in the number of existing cases of diabetes in Hong Kong, the disease burden will remain profound. Our results underscore the need to intensify health care efforts targeting disease awareness, broader screening and aggressive risk factor management in this patient group in whom adverse outcomes are highly preventable.” – by Amber Cox
Disclosure: The researchers report no relevant financial disclosures.
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