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Top 5 online reproduction/androgen disorders stories, videos from 2015
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Endocrine Today has compiled a list of the top 5 reproduction/androgen stories and videos posted in 2015.
Healio.com/Endocrinology readers were interested in white matter microstructure altering PCOS, the effect of endocrine disrupters, management of PCOS, and more.
White matter microstructure altered in PCOS
In adults with polycystic ovary syndrome, white matter microstructure is altered and cognitive performance is compromised, according to study findings published in The Journal of Clinical Endocrinology & Metabolism.
“PCOS was associated with both subtle decrements of cognitive function and alterations in microstructure of brain white matter,” the researchers wrote. “These differences are not attributable to BMI, which was closely matched between groups, as was general intelligence.” Read more.
New insight on “cocktail effect” of endocrine disruptors
In an article published in Nature Communications, researchers identified a molecular mechanism that could contribute to the “cocktail effect” of endocrine disruptors.
“Humans are chronically exposed to multiple exogenous substances, including environmental pollutants, drugs and dietary components,” the researchers wrote. “Many of these compounds are suspected to impact human health, and their combination in complex mixtures could exacerbate their harmful effects.” Read more.
VIDEO: Managing PCOS requires commitment to being healthy
PHILADELPHIA — Katherine Sherif, MD, director of Jefferson Women’s Primary Care and vice chair of the Department of Medicine at Thomas Jefferson University Hospitals in Philadelphia, describes the five components of a treatment plan for managing PCOS.
A nutrition plan incorporating fewer calories and carbohydrates, a strength-based exercise program, adequate sleep, evidence-based alternative therapies and appropriate medication use are key elements to managing PCOS. Watch video.
Lifestyle changes plus metformin linked to weight loss, improved symptoms for PCOS
A combination of lifestyle changes plus metformin in women with polycystic ovary syndrome may lead to better rates of weight loss and greater clinical improvements than lifestyle modification alone, according to research in Human Reproduction Update.
In a systematic review and meta-analysis of studies comparing lifestyle changes and metformin use in women with PCOS, researchers found that women who added metformin to lifestyle changes had more weight loss, lower BMI and improved menstruation compared with those assigned lifestyle changes and placebo. Read more.
VIDEO: Name change sought for PCOS
PHILADELPHIA — Anuja Dokras, MD, PhD, director of the PENN Polycystic Ovary Syndrome Center in the University of Pennsylvania Health System in Philadelphia, explains that the name polycystic ovary syndrome does not appropriately describe the condition.
Women with PCOS do not, in fact, have ovarian cysts, and the name has shifted emphasis from other issues associated with the condition, including hypertension, diabetes, weight concerns and high cholesterol, according to Dokras. Watch video.