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Depression, eating disorders associated with diabetes
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Depression and eating disorders were significantly associated with diabetes diagnosis, according to recently published data in Diabetologia.
“The magnitude of the association between depression and diabetes diagnosis was about 40% increased risk in unadjusted analyses and 30% in adjusted analyses,” researchers wrote.
They examined this link between 16 pre-existing Diagnostic Statistical Manual, 4th edition (DSM-IV) mental disorders to a self-reported diagnosis of diabetes through a series of cross-sectional in-person household surveys using the WHO Composite International Diagnostic Interview. Patients included community-dwelling adults (n=52,095) from 19 countries.
The researchers identified 2,580 patients with adult-onset diabetes. Within this subgroup, 11.3% had major depression, 7% had specific phobia and 5.8% abused alcohol. The mean age of onset for the mental disorders ranged from 9.3 to 31.6 years, researchers wrote. The lowest mean onset age for specific phobia was 9.3 years, whereas social phobia presented at age 13.7 years and bulimia nervosa at 15.6 years.
“The two eating disorders, binge eating disorder and bulimia nervosa, stand out as having a particularly strong association with diabetes (OR=3.8 and 3.9, respectively),” researchers wrote.
In bivariate models, all of the 16 DSM-IV mental disorders were tied to a diabetes diagnosis.
However, only depression (OR=1.3; 95% CI, 1.1-1.5), intermittent explosive disorders (OR=1.6; 95% CI, 1.1-2.1), binge eating disorder (OR=2.6; 95% CI, 1.7-4) and bulimia nervosa (OR=2.1; 95% CI, 1.3-3.4) continued after adjustments for comorbidities, according to data.
Disclosure: Three researchers report multiple relevant financial disclosures. See the study for a full list of disclosures.
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