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Diabetes before, during pregnancy associated with risk for depression

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Low-income women with diabetes were at higher risk for depression during pregnancy or after birth compared with women without diabetes.

The researchers conducted a retrospective study using data from 11,024 women who gave birth between July 1, 2004 and Sept. 30, 2006.

Depression during pregnancy or postpartum was observed in 15.2% (n=100) of women with pre-pregnancy or gestational diabetes and in 8.5% (n=886) of women without diabetes. When adjusted for several variables including age and race, women with diabetes had nearly twice the risk for depression compared with women without diabetes (OR=1.85; 95% CI, 1.45-2.36), according to the study.

The odds of being diagnosed with postpartum depression or taking an antidepressant medication during the year after giving birth was higher among women with diabetes and no prenatal indication of depression than among women without diabetes (OR=1.69; 95% CI, 1.27-2.23).

JAMA. 2009;301:842-847.