December 09, 2008
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Depression linked with abdominal obesity

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Symptoms of depression may lead to increases in abdominal obesity, according to findings from the Health, Aging and Body Composition Study.

Researchers examined depressive symptoms and obesity in 2,088 adults aged 70 to 79 years. They used the Center for Epidemiological Studies Depression score of 16 or higher to define baseline depression.

During five years of follow-up, the researchers observed an association between baseline depression score and increases in visceral fat (P=.001) and sagittal diameter (P=.01) after adjusting for sociodemographics, lifestyle, diseases and overall obesity. According to the study, the increase in abdominal obesity was independent of overall obesity.

“There may be specific pathophysiological mechanisms that link depression with visceral fat accumulation … these results might also help explain why depression increases the risk for diabetes and cardiovascular disease,” the researchers wrote.

Arch Gen Psychiatry. 2008;65:1386-1393.