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Women unsatisfied with osteoporosis therapy more likely to switch, discontinue treatment

Issue: October 2009

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Twenty-five percent of women reported discontinuation of initial osteoporosis therapy within the first year, and 7% reported switching to another therapy, according to results of POSSIBLE US, a prospective registry study.

Based on questionnaire responses from 5,015 women, those less satisfied with the convenience of their therapy were 39% (HR=0.72) more likely to discontinue or switch initial therapy, and women less satisfied with effectiveness were 25% (HR=0.80) more likely to discontinue or switch. Among women who reported moderate/severe adverse events, those less satisfied with treatment were 61% (HR=0.62) more likely to discontinue or switch.

For more information:

• Do T. SA0317. Presented at: American Society for Bone and Mineral Research 31st Annual Meeting; September 11-15, 2009; Denver.