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Sedentary time negatively associated with cardiometabolic, inflammatory biomarkers
Healy GN. Eur Heart J. 2011;doi:10.1093/eurheartj/ehq451.
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Taking many breaks from sedentary time, even just 1-minute breaks, appeared to result in lower levels of C-reactive protein and smaller waist circumferences.
Researchers from University of Queensland in Australia also found that prolonged periods of sedentary time, even in those who exercised regularly, were associated with larger waist circumferences, lower levels of HDL, higher levels of C-reactive protein (CRP) and higher triglycerides.
The cross-sectional study was conducted in participants of the National Health and Nutrition Examination Survey between 2003 and 2006. The sample included 4,757 adults who wore accelerometers and had sufficient data. Researchers measured waist circumference, blood pressure, cholesterol levels and CRP levels. A sub-sample of 2,118 participants was available for fasting analyses for triglycerides, plasma glucose and insulin.
The participants wore the accelerometer for 14.6 hours per day. The average time spent sedentary was 8.44 hours. Women were more sedentary; however, they took additional breaks and had a more favorable cardiometabolic profile compared with men.
“These population-based findings provide further evidence on the deleterious associations of sedentary time with cardiometabolic health in adults, and provide novel evidence on the relationship of sedentary time with the inflammatory biomarker CRP,” the researchers wrote. “In general, these associations were consistent across sex, age and race/ethnicity.”
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