October 02, 2014
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HF events preceded by worsening rapid shallow breathing

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LAS VEGAS — In a new study, patients who experienced HF-related hospitalization or required unscheduled outpatient HF treatment exhibited worsening rapid shallow breathing in the 7 days before the event.

At the Heart Failure Society of America Annual Scientific Meeting, researchers presented data on 52 adults enrolled in the MultiSENSE trial, a nonrandomized feasibility study designed to evaluate the ability of multiple sensors in an implantable cardioverter defibrillator to detect early signs of worsening HF. The mean age of the patients was 66.4 years and 72.7% were men. All patients had been implanted with Cognis cardiac resynchronization therapy defibrillators (CRT-Ds; Boston Scientific).

Researchers assessed the incidence of HF-related hospitalization and unscheduled clinic visits for HF-related therapy with IV diuretics, and calculated mean values of respiratory rate, minute ventilation, relative tidal volume and rapid shallow breathing index for the 7 days before each HF event as compared with values collected 35 to 63 days before each event.

In total, 69 HF events were recorded. The daily mean respiratory rate was significantly higher before HF events (2.2%; P=.03). The researchers observed no significant differences in relative minute ventilation or relative tidal volume before an event.

Daily values for the rapid shallow breathing index increased by 6% during the pre-event periods (P=.01), with the largest change observed in respiratory parameters.

“Data from MultiSENSE show that rapid shallow breathing, measured by respiratory rate and the [rapid shallow breathing index], changes significantly before HF events,” Eric D. Popjes, MD, of Penn State Hershey Heart and Vascular Institute, said during a presentation. “Perhaps these parameters, when combined with other diagnostic measures, may be able to provide additional information … and identify [events] relatively early.” – by Adam Taliercio

For more information:

Capucci A. Abstract #038. Presented at: the Heart Failure Society of America Annual Scientific Meeting; Sept. 14-17, 2014; Las Vegas.

Disclosure: The study was sponsored by Boston Scientific.