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March 01, 2022
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Health care resource use greater among patients with asthma, comorbidities

PHOENIX — Chronic rhinosinusitis and bronchiectasis as comorbidities in patients with asthma were associated with higher health care use, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.

“We examined the use of oral corticosteroids, antibiotic courses and emergency room visits or hospitalizations associated with these conditions,” Margaret S. Kim, MD, a clinical fellow in allergy and immunology at Northwestern Medicine in Chicago, said in an AAAAI-issued press release. “Asthma patients with both [chronic rhinosinusitis] and bronchiectasis had a higher odds ratio for all of the factors.”

Emergency Room Sign
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Using electronic medical records between 1988 and 2021, ICD codes and CT scan reports, Kim and colleagues identified 5,038 patients with asthma, including 1,979 (39%) with comorbid chronic rhinosinusitis and 967 (19%) with comorbid non-cystic fibrosis bronchiectasis.

A total of 496 patients (9.8%) had both comorbidities.

After controlling for age, sex and race, patients with asthma and both chronic rhinosinusitis and bronchiectasis had a higher likelihood for oral corticosteroid use (OR = 2.3; 95% CI, 1.7-2.9), antibiotic use (OR = 3; 95% CI, 2.3-3.9) and ED visit or hospitalizations (OR = 1.6; 95% CI, 1.2-2.1) compared with those with bronchiectasis but without chronic rhinosinusitis.

“The presence of chronic rhinosinusitis in patients with asthma and bronchiectasis identifies a subset of patients with high health care utilization and represents an important comorbidity for which to screen,” Kim and colleagues wrote in the abstract.

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