July 22, 2015
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Self-reported adverse reactions to common foods higher in adults with asthma

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Individuals with asthma more frequently report adverse reactions to foods than people without asthma, according to study results.

The researchers also reported patients with asthma more frequently showed immunoglobulin-E reactivity to common foods.

“We also show that asthmatics reported symptoms from the gastrointestinal-tract in a greater frequency compared to non-asthmatics and the most common foods causing self-reported symptoms were nuts, fruits, milk, dairy products, alcohol, peanuts and shellfish,” Georgios Rentzos, MD, allergist at the University Hospital of Sahlgrenska in Sweden, and colleagues wrote. “The non-asthmatic subjects seem to report adverse reaction to the same food items as asthmatics but at a significantly lower frequency.”

Rentzos and colleagues conducted a cross sectional study on 1,527 participants aged 18 to 75 years to determine the commonness of self-reported adverse reactions and immunoglobulin-E (IgE) sensitization to different foods as well as the occurrence of food-related gastrointestinal symptoms in adults with and without asthma.

Participants with asthma (n = 583) reported a significantly higher prevalence of adverse reactions to food (53.1%) than people without asthma (29.8%) (P < .001).

The most common foods participants with asthma experienced adverse reactions to included hazelnut (20.5%), apple (17.5%) and kiwi (14.3%).

The researchers reported that participants with asthma also expressed more gastrointestinal symptoms to foods including hazelnut (13% vs. 5.2%, P < .001), apple (11.4% vs. 6%, P < .001) and milk (10.4% vs. 5.7%, P < .01).

The researchers also noted participants with asthma are more frequently sensitized to the foods tested in the study than participants without asthma (38.2% vs. 13.9%, P < .001).

There are some limitations to the study, according to the researchers.

“It is well known that self-reported food intolerance yield a much higher prevalence compared to prevalence from performed food challenges and IgE data for food allergies,” the researchers wrote. – by Ryan McDonald

Disclosure: The researchers report no relevant financial disclosures.