White Matter
Pathophysiology
White, gray matter MRI abnormalities linked to risk for late-onset epilepsy
PHILADELPHIA — In older adults, the presence of white and gray matter abnormalities on MRI is linked to greater risk for late-onset epilepsy, according to a poster presentation.
Circuit-based lesion analysis may help diagnose memory, other deficits in MS
Tracking data from white matter lesions on structural imaging via a circuit-based approach may assist in prognosis of memory and other higher order deficits for those with multiple sclerosis, per research published in Journal of Neurology.
FDA grants 510(k) clearance for software to image the brain’s white matter
The FDA has granted 510(k) clearance to a Canadian neuroimaging company for its quantitative imaging software, which assists neurologists and radiologists dealing with brain white matter issues for adjunctive care.
OCT measures linked to neurodegeneration, disability in patients with MS
Peripapillary retinal nerve fiber layer thickness and ganglion cell/inner plexiform layer volume are key OCT markers of neurodegeneration and disability in patients with multiple sclerosis, according to data in the Journal of Neurology.
Increases in myelin, white matter reported at 6 months with Canavan disease gene therapy
Myrtelle Inc. has reported promising 6-month trial data for a recombinant adeno-associated virus vector-based investigational gene therapy for Canavan disease.
Vasomotor symptoms linked to midlife brain health
Women who experienced vasomotor symptoms had elevated whole brain volume of white matter hyperintensities, which can affect brain health, data presented at the NAMS Annual Meeting showed.
Sleep apnea changes associated with cognitive impairment, brain structure alterations
Changes in obstructive sleep apnea status were linked with white matter integrity and cognitive performance, suggesting that timely intervention of OSA could help preserve brain health, researchers reported in JAMA Network Open.
White matter hyperintensity tied to menopause
Postmenopausal women had a greater burden of white matter hyperintensity — or WMH — compared with men and premenopausal women, as well as a faster increase in WMH, according to a cross-sectional analysis of the Rhineland Study.
MMA fighting linked to increased white matter hyperintensity volume in brain
NEW ORLEANS - Mixed martial arts sparring was associated with increased white matter hyperintensity volume and a large caudate region, suggesting some protective function, a researcher said at the American Psychiatric Association annual meeting.