White Matter

Alterations in white matter integrity were linked to cognitive impairment, and associations were strongest in those with major depressive disorder compared with healthy controls, according to new research.

PHILADELPHIA — In older adults, the presence of white and gray matter abnormalities on MRI is linked to greater risk for late-onset epilepsy, according to a poster presentation.

Tracking data from white matter lesions on structural imaging via a circuit-based approach may assist in prognosis of memory and other higher order deficits for those with multiple sclerosis, per research published in Journal of Neurology.

The FDA has granted 510(k) clearance to a Canadian neuroimaging company for its quantitative imaging software, which assists neurologists and radiologists dealing with brain white matter issues for adjunctive care.

Peripapillary retinal nerve fiber layer thickness and ganglion cell/inner plexiform layer volume are key OCT markers of neurodegeneration and disability in patients with multiple sclerosis, according to data in the Journal of Neurology.

Myrtelle Inc. has reported promising 6-month trial data for a recombinant adeno-associated virus vector-based investigational gene therapy for Canavan disease.

Women who experienced vasomotor symptoms had elevated whole brain volume of white matter hyperintensities, which can affect brain health, data presented at the NAMS Annual Meeting showed.

Changes in obstructive sleep apnea status were linked with white matter integrity and cognitive performance, suggesting that timely intervention of OSA could help preserve brain health, researchers reported in JAMA Network Open.

Postmenopausal women had a greater burden of white matter hyperintensity — or WMH — compared with men and premenopausal women, as well as a faster increase in WMH, according to a cross-sectional analysis of the Rhineland Study.