White Matter

Children with ADHD exhibited modest differences on structural brain measures compared with peers without ADHD, according to results of a cross-sectional population-based study published in The Lancet Psychiatry.

White matter hyperintensity volumes at 1 year strongly correlated with contemporaneous cognitive scores after stroke, according to study results published in Neurology.

In patients aged 50 years and older, silent brain infarction and white matter disease were common and correlated with significant increases in risk for subsequent symptomatic stroke, according to a study published in Neurology.

Variances in amyloid positivity across nine subgroups of patients, who were classified according to cognitive states and white matter hyperintensity levels, suggested Alzheimer’s and cerebral small vessel diseases exist on a continuum.

White matter hyperintensity volume, type and shape correlated with an increased risk for mortality and ischemic stroke among patients with manifest arterial disease, according to findings from the SMART-MR study published in Neurology.

Increased white matter hyperintensities occurred frequently among patients with behavioral-variant frontotemporal dementia and Alzheimer’s disease in a cross-sectional MRI study published in Neurology.

A recent study in patients with Parkinson’s disease highlighted the link between visual dysfunction and cognitive decline, as well as greater white matter degeneration. The FDA also approved Gocovri extended-release tablets for patients with PD. Read these and more recent stories below.

Patients with Parkinson’s disease and visual dysfunction had a higher risk for cognitive impairment and greater white matter degeneration compared with those without visual dysfunction, according to results published in Movement Disorders.

Heavy alcohol consumption during adolescence appeared associated with deleterious effects on white matter microstructural integrity, according to results of a case-control study published in JAMA Psychiatry.

BP and hypertension may be associated with risk for white matter lesions in atrial fibrillation but not with large noncortical or cortical infarcts, according to data published in Hypertension.