University Of California San Francisco
Cancer drugs approved based on OS vs. surrogate outcomes have lowest median annual cost
Cancer drugs that received approval based on increased OS compared with other measures had the lowest median annual cost, according to a research letter published in JAMA Internal Medicine.
Postload glucose levels tied to incident AF in older women
In older adults, elevated postload glucose levels were associated with incident atrial fibrillation, particularly in women, researchers reported in Heart.
Sacituzumab govitecan extends survival regardless of Trop-2 expression in breast cancer
SAN ANTONIO — Sacituzumab govitecan prolonged survival compared with physician’s choice of therapy among patients with heavily pretreated breast cancer, according to results presented at San Antonio Breast Cancer Symposium.
Corticosteroid injections may lead to progression of knee OA
Results presented at the Radiological Society of North America Annual Meeting showed corticosteroid injections may be associated with progression of knee osteoarthritis as assessed semi-quantitatively by whole-organ MRI scores.
Black, Asian infants with cystic fibrosis more likely to be missed on newborn screening
Black and Asian infants with cystic fibrosis had the lowest rates of detection during newborn screening, whereas white infants had the highest rates, according to a study published in Pediatric Pulmonology.
Military personnel exposed to inorganic dust at risk for COPD
Researchers found a 25% increased risk for COPD among U.S. military veterans who took part in duties that had moderate or high likelihoods of exposure to inorganic dust, according to a research letter published in Chest.
Q&A: Trial to assess phage therapy in patients with cystic fibrosis
A trial to assess bacteriophage, or “phage,” therapy, which utilizes a virus to target specific bacteria and leave behind other bacteria and human cells, is underway among patients with cystic fibrosis, according to an NIH press release.
Nearly two-thirds of patients with rheumatoid arthritis have at least one sleep disorder
Nearly two-thirds of patients with rheumatoid arthritis meet the criteria for at least one sleep disorder, according to data published in Arthritis Care & Research.
Q&A: The root causes of problems in primary care
“Financial neglect and excessively large patient panels” are the root causes of problems in primary care, according to Thomas Bodenheimer, MD, MPH, a professor of family and community medicine at the University of California, San Francisco.
E-cigarettes confer endothelial dysfunction similar to traditional cigarettes
Reduced flow-mediated dilation was observed among both e-cigarette and traditional cigarette users, but circulating levels of certain inflammatory and thrombotic mediators differed between the two groups, researchers reported.