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Terlipressin

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November 21, 2022
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Terlipressin reduced need for renal replacement therapy 1 year after liver transplant

Terlipressin reduced need for renal replacement therapy 1 year after liver transplant

CHARLOTTE, N.C. — A subgroup analysis of liver transplant patients with hepatorenal syndrome type 1 demonstrated that terlipressin decreased the need for renal replacement therapy up to 12 months following transplantation.

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October 10, 2022
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Terlipressin should be used with caution in hepatorenal syndrome type 1, grade 3 ACLF

Terlipressin should be used with caution in hepatorenal syndrome type 1, grade 3 ACLF

Patients with hepatorenal syndrome type 1 and advanced acute-on-chronic liver failure had significantly greater incidence of respiratory failure and 90-day mortality when treated with terlipressin vs. placebo, according to research.

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November 24, 2021
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VIDEO: Serum creatinine linked to adverse events in HRS-AKI treated with terlipressin

VIDEO: Serum creatinine linked to adverse events in HRS-AKI treated with terlipressin

In this exclusive video, Andrew Allegretti, MD, MSc, discussed a post hoc analysis assessing serum creatinine in patients treated with terlipressin for hepatorenal syndrome-acute kidney injury.

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November 03, 2021
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VIDEO: Terlipressin safe, effective for esophageal bleeding, liver cirrhosis

VIDEO: Terlipressin safe, effective for esophageal bleeding, liver cirrhosis

LAS VEGAS — In this video exclusive, Kevin Moore, MD, discussed a study assessing real-world outcomes in patients with esophageal variceal hemorrhage and liver cirrhosis treated with terlipressin.

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November 20, 2020
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VIDEO: Early treatment with Terlipressin benefits patients with hepatorenal syndrome

VIDEO: Early treatment with Terlipressin benefits patients with hepatorenal syndrome

In this exclusive video, Andrew Allegretti, MD, MSc, discusses his poster from The Liver Meeting Digital Experience that explored factors associated with response to terlipressin treatment in patients with hepatorenal syndrome.

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September 16, 2020
1 min read
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FDA: More data needed to approve terlipressin NDA for hepatorenal syndrome type 1

FDA: More data needed to approve terlipressin NDA for hepatorenal syndrome type 1

Although the FDA accepted a new drug application for terlipressin to treat hepatorenal syndrome type 1, the agency has issued a complete response letter to Mallinckrodt plc stating that more data are required before the NDA can be approved.

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July 16, 2020
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FDA recommends approval of terlipressin for treatment of HRS-1 despite concerns

FDA Cardiovascular and Renal Drugs Advisory Committee voted 8-7 to recommend approval of terlipressin for the treatment of hepatorenal syndrome type 1 in patients with cirrhosis.

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June 12, 2020
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Study shows terlipressin improves kidney function in hepatorenal syndrome

Study shows terlipressin improves kidney function in hepatorenal syndrome

Newly published research from the United Kingdom demonstrates terlipressin is effective for improving kidney function in hospitalized patients with hepatorenal syndrome type 1.

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November 12, 2019
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Terlipressin demonstrates ‘major advance’ in hepatorenal syndrome treatment

Terlipressin demonstrates ‘major advance’ in hepatorenal syndrome treatment

BOSTON — In this exclusive video from The Liver Meeting 2019, Arun Sanyal, MD, professor of medicine at Virginia Commonwealth University, discusses results of the CONFIRM trial, which demonstrated that terlipressin was effective in improving renal function and achieving hepatorenal syndrome reversal in a significant percentage of patients with hepatorenal syndrome type 1.