Probiotic

In this exclusive video, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, discussed two strains of probiotics that the company is currently looking at. Patients with type 2 diabetes are missing strains to enable metabolizing fiber and albuterate and to regulate the mucin layer. Cutcliffe said Pendulum has developed a probiotic, which in a randomized placebo-controlled trial showed efficacy is patients with type 2 diabetes and dropped glucose by 30%.

In this exclusive video, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, discussed the latest findings regarding the microbiome.

Previous reports indicated that in-hospital famotidine use was associated with a reduced risk for morality among patients with COVID-19; however, a new study found no correlation. It was the top story in gastroenterology last week.

Probiotics are used by millions of people around the world. Sales in the United States alone are expected to grow to more than $6 billion in 2020. Despite their wide reach in the consumer market, scientific data on probiotics’ real benefit have been lacking.

The lead article on the use of probiotics in gastroenterology highlights a conundrum that we have all been dealing with in the trenches for at least decade.

Patients with celiac disease who use probiotics may experience improvements in gastrointestinal symptoms, according to results published in the American Journal of Gastroenterology.

Although patients on hemodialysis who received probiotics had decreases in idoxyl sulfate levels, researchers observed no benefits of supplementation on other studied measures, including insulin resistance and cholesterol-triglyceride ratio.

A probiotic supplement with two strains of bifidobacteria was associated with increased insulin sensitivity and lower BMI for children with obesity, according to study data.

Probiotics alone or combined with prebiotics may alleviate depression, according to results of a systematic review published in BMJ Nutrition, Prevention & Health.

Fecal microbiota transplantation was safe and effective for the treatment of Clostridioides difficile infection in patients with cirrhosis, according to study results.