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Nonalcoholic Fatty Liver Disease

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April 18, 2020
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Correlations between metal ion transporters, liver MRIs identify mechanism of steatohepatitis

The link between two metal ion transporters and MRI based corrected Tl demonstrated a new mechanism in steatohepatitis, according to a recently published article.

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April 11, 2020
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Positive anti-HBc linked to cirrhosis, hepatocellular carcinoma in NAFLD

For patients with nonalcoholic fatty liver disease, a positive anti-hepatitis B core antibody was correlated with cirrhosis and hepatocellular carcinoma, according to a study published in the American Journal of Gastroenterology.

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March 13, 2020
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Fatty liver negatively affects beta-cell function

Fatty liver negatively affects beta-cell function

Beta-cell function may deteriorate in the presence of excess fat in the liver for adults with and without diabetes, according to findings published in the Journal of Diabetes Investigation.

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February 06, 2020
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Fibrosis linked with mortality, liver-related morbidity risk in patients with NAFLD

Biopsy-confirmed fibrosis was associated with risk for mortality and liver-related morbidity in patients with NAFLD, regardless of confounding factors and in patients with NASH, according to study results.

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January 29, 2020
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Antisense oligonucleotide therapy for triglyceride reduction shows positive top-line results

Antisense oligonucleotide therapy for triglyceride reduction shows positive top-line results

Akcea Therapeutics and Ionis Pharmaceuticals announced that a phase 2 study of AKCEA-ANGPTL3-LRx for the treatment of patients with hypertriglyceridemia, type 2 diabetes and nonalcoholic fatty liver disease met its primary endpoint of significant triglyceride lowering.

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January 27, 2020
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Biologic therapy holds promise to thwart adverse CV events in psoriasis

MAUI, HAWAII — A novel study that examined the link between psoriasis and CVD was one of several studies summarized at Maui Derm for Dermatologists 2020 that examined psoriasis’ link to several co-morbidities.

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January 27, 2020
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Individuals with alcohol use disorder have an increased fibrosis risk

The risk of fibrosis is highest in young adults with harmful drinking patterns and steatosis, according to data from a population-based study.

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January 14, 2020
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Interim analysis of metabolic modulators shows efficacy in NAFLD

Axcella released an update from the ongoing clinical study of two potential therapies for nonalcoholic fatty liver disease that showed the compounds were safe, well-tolerated, and demonstrated relevant clinical response, according to a press release.

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January 09, 2020
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NASHNET designates eighth center of excellence

NASHNET has designated the Central Virginia VA Health Care System as its eighth founding charter member and “center of excellence” in recognition of the system’s work in fatty liver disease, according to a press release.

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January 08, 2020
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Histological noninvasive tools define distinct profiles between NAFLD, NASH

Both the fatty liver inhibition of progression algorithm and the steatosis activity and fibrosis scoring system identified distinct clinical and biological profiles of disease severity among patients with suspected nonalcoholic fatty liver disease.

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