Massachusetts General Hospital

CHICAGO — First-line use of cyclin-dependent kinase 4/6 inhibitors did not confer significant benefit vs. second-line use when added to endocrine therapy for women with hormone receptor-positive, HER2-negative, advanced breast cancer.

CHICAGO — The addition of tumor-treating fields to second-line therapy prolonged survival for patients with metastatic non-small cell lung cancer whose disease progressed on or after platinum therapy, according to results presented at ASCO Annual Meeting.

A leadless, ultrasound-based endocardial pacing system was able to deliver cardiac resynchronization therapy to patients unable to be implanted with conventional CRT devices, researchers reported.

Development and use of oral chemotherapy medications has increased substantially over the past decade, offering many patients with cancer a more convenient and less stressful treatment option.

The BCG vaccine appeared associated with a significantly lower rate of and risk for Alzheimer’s disease and related dementias among patients with nonmuscle-invasive bladder cancer, according to data published in JAMA Network Open.

Adolescents and young adults with obesity who undergo sleeve gastrectomy have declines in bone strength and volumetric bone mineral density 1 year after surgery, according to study data.

Patients with hematologic malignancies reported significant improvement in quality of life after receiving chimeric antigen receptor T cells, results from a longitudinal study in Blood Advances showed.

Being younger at menopause onset and initiating hormone therapy after more than 5 years were both linked to increased tau vulnerability among women, according to a cross-sectional study published in JAMA Neurology.

Mothers who contract COVID-19 during pregnancy are more likely to have infants with a lower birth weight and greater weight gain during the first year of life compared with mothers who did not have COVID-19, according to study data.

LAS VEGAS — In this video from the American Academy of Orthopaedic Surgeons Annual Meeting, Andrew J. Schoenfeld, MD, discussed the cost-utility benefits of robotic assistance for adult spinal deformity procedures.