Major Depressive Disorder

Major depressive disorder and noncombat trauma can serve as identifiers of suicide ideation risk among United States Army soldiers during combat deployment, according to results of a survey study published in JAMA Network Open.

Researchers have developed a tool with predictive potential for identifying adolescents who are at high or low risk for depression in young adulthood, according to findings from a Brazilian cohort that were published in Journal of the American Academy of Child & Adolescent Psychiatry.

An interactive voice response system that uses artificial intelligence effectively monitored the well-being of patients with serious mental illness, according to study findings published in PLOS One.

Children and adolescents who are at high risk for bipolar disorder achieved longer times between mood episodes after receiving family-focused therapy, according to results of a randomized clinical trial published in JAMA Psychiatry.

Findings of the largest genome-wide association study of anxiety traits to date have revealed new insights into genetic risk mechanisms shared by anxiety and related psychiatric disorders, researchers wrote in American Journal of Psychiatry.

The six-item Hamilton Depression Rating Scale, or HAM-D6, was a better measure of core depressive symptoms than the 17-item HAM-D17, according to results of a post hoc analysis of a randomized controlled trial published in BMC Psychiatry.

Electroencephalographic, or EEG, data may serve as an effective treatment planning tool for patients with depression, according to results of a prognostic study published in JAMA Network Open. Researchers analyzed this data’s effectiveness regarding the antidepressant escitalopram.

Resting-state functional MRI metrics measured at age 7 years can be used to predict the developmental trajectory of ADHD and major depressive disorder symptoms at age 11 years, making these measurements “promising biomarkers” for the early identification of children at risk for developing these disorders, according to findings of a longitudinal cohort study published in JAMA Psychiatry.

Published findings determined that, for patients with chronic kidney disease and major depressive disorder, higher concentrations of the inflammatory biomarker hsCRP were associated with both improvement and response to the antidepressant sertraline.

Adults with diabetes and depressive disorder treated with antidepressant drugs experienced fewer episodes of hyperglycemic crisis than those not taking antidepressant medications, according to findings published in the Journal of Diabetes and its Complications.