Major Depressive Disorder

An updated version of an established model for major depressive disorder offers a “useful foundation” toward a comprehensive developmental model of prescription opioid use disorder, according to study results published in Journal of Clinical Psychiatry.

Young people with type 1 diabetes should be screened for suicidal thoughts, as suicide had been attempted by 16.3% of individuals in a cohort of young people with type 1 diabetes who had such thoughts, according to findings published in Diabetes Care.

Research presented at the annual meeting of the Academy of Managed Care Pharmacy — AMCP Nexus 2019 — underscored the significantly higher costs for privately insured adult patients diagnosed with major depressive disorder and suicide ideation/attempt than adults without MDD.

Experiential avoidance is a predictor for major depressive disorder and generalized anxiety disorder symptomatology in older adolescents, data from an observational, longitudinal study published in the Journal of Clinical Psychiatry suggest.

Among people with a genetic predisposition for depression, 4 additional hours of physical activity may reduce the odds of incident depression by 17%, according to results of a biobank cohort study published in Depression & Anxiety.

A combinatorial pharmacogenomic test significantly improved outcomes among patients with major depressive disorder who had at least one prior medication failure, according to results of a randomized controlled trial published in The Journal of Clinical Psychiatry.

SAN FRANCISCO — Open globe injuries are associated with an increased risk for anxiety and depression, according to a poster at the American Society of Ophthalmic Plastic and Reconstructive Surgery meeting.

Current evidence does not support claims of adverse health outcomes associated with antidepressant use, and such claims are likely exaggerated by confounding by indication, according to findings from a systematic umbrella review published in JAMA Psychiatry.

SAN DIEGO — In a video interview, W. Clay Jackson, MD, DipTh, clinical assistant professor of family medicine and psychiatry, University of Tennessee College of Medicine, talked about his presentation on the treatment of major depressive disorder with comorbid disorders.

SAN DIEGO — An expert discussed the research supporting ketamine and esketamine for treatment-resistant depression as well as what future research should focus on in a session presented at Psych Congress.