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Lung Function

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December 26, 2023
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Top 10 COPD stories of 2023

Top 10 COPD stories of 2023

Healio Pulmonology has compiled the top news on COPD posted in 2023.

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December 19, 2023
3 min read
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Rademikibart improves lung function in moderate to severe asthma

Rademikibart improves lung function in moderate to severe asthma

Adults with moderate to severe persistent asthma receiving rademikibart every 2 weeks showed greater improvements in lung function at week 12 compared with patients assigned placebo, according to topline results from a phase 2b trial.

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December 13, 2023
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Severe OSA linked to poorer lung function over time

Severe OSA linked to poorer lung function over time

Over time, adults with severe obstructive sleep apnea had more high attenuation areas on CT and lower lung function, which may signal early interstitial lung disease, according to data published in Annals of the American Thoracic Society.

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November 28, 2023
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Dupilumab improves lung function, reduces exacerbations in COPD with type 2 inflammation

Dupilumab improves lung function, reduces exacerbations in COPD with type 2 inflammation

Adults with moderate to severe COPD and type 2 inflammation receiving dupilumab vs. placebo had fewer exacerbations and improved lung function at 52 weeks, according to topline results from the phase 3 NOTUS trial.

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November 20, 2023
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Odds for COPD in young population increase with ozone, household air pollution exposure

Odds for COPD in young population increase with ozone, household air pollution exposure

Individuals aged 15 to 50 years faced heightened odds for COPD if they had been exposed to household air pollution and elevated ambient ozone levels, according to results published in Thorax.

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November 17, 2023
4 min read
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Intravenous alpha-1 antitrypsin improves survival in patients with deficiency

Intravenous alpha-1 antitrypsin improves survival in patients with deficiency

Patients with severe alpha-1 antitrypsin deficiency had improved survival with intravenous plasma-purified alpha-1 antitrypsin therapy, according to results published in American Journal of Respiratory and Critical Care Medicine.

News
November 08, 2023
3 min read
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Aerosol gene therapy safe, heightens CFTR protein levels in cystic fibrosis

Aerosol gene therapy safe, heightens CFTR protein levels in cystic fibrosis

Receipt of 4D-710, an aerosolized gene therapy, resulted in high cystic fibrosis transmembrane conductance regulator protein expression levels in patients with cystic fibrosis, according to a company press release.

News
November 03, 2023
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Q&A: Establishing global standard for exercise testing in patients with cystic fibrosis

Q&A: Establishing global standard for exercise testing in patients with cystic fibrosis

For patients with cystic fibrosis, exercise helps with disease management, and exercise tests allow clinicians to assess lung health, muscle strength and treatment response, according to a press release from University of Portsmouth.

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October 30, 2023
3 min read
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Propylene oxide lowers lung function in urban residents

Propylene oxide lowers lung function in urban residents

Residents in urban areas experienced reductions in lung function when exposed to increased levels of propylene oxide, according to study results published in CHEST.

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October 26, 2023
1 min read
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FDA grants breakthrough designation to progressive pulmonary fibrosis treatment

FDA grants breakthrough designation to progressive pulmonary fibrosis treatment

The FDA granted breakthrough therapy designation to an oral lysophosphatidic acid receptor 1 antagonist that lowered the rate of percent-predicted FVC decline among patients with progressive pulmonary fibrosis.

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