Levothyroxine

Nearly one-third of older adults on thyroid hormone also take another medication that can interfere with thyroid function tests, particularly adults with multiple comorbidities, according to data presented at the ENDO annual meeting.

A subset of patients with hypothyroidism report dissatisfaction with treatment and persistent symptoms, such as fatigue and weight gain, despite medication, but there are steps endocrinologists can take to help, according to a speaker.

The risk for testing positive for COVID-19 or developing more severe disease does not differ between adults treated for hypothyroidism or hyperthyroidism and euthyroid controls, according to a Danish database analysis.

Three large professional thyroid organizations issued a joint statement calling for new trials of combination therapy to treat hypothyroidism, citing new clinical endpoints and the importance of assessing patient-reported outcomes.

Central hypothyroidism is prevalent in about 1 in 2 adults with Cushing’s syndrome, and thyroid function can be restored after curative surgery for most patients, according to study findings.

A majority of adults with hypothyroidism responding to a survey said they were dissatisfied with treatment and reported having a low quality of life score, according to study data published in Clinical Endocrinology.

More than one-third of individuals taking thyroid hormone replacement remained euthyroid after discontinuing their medication, according to study findings published in Thyroid.

A cohort of pregnant women in Canada who were overtreated for hypothyroidism with levothyroxine were more likely to have a preterm delivery than women with normal thyroid-stimulating hormone, according to a study published in Thyroid.

Acella Pharmaceuticals is voluntarily recalling one lot of 15 mg and one lot of 120 mg levothyroxine and liothyronine tablets due to subpotency, according to an FDA announcement.

Among patients with subclinical hypothyroidism and acute MI, treatment with levothyroxine demonstrated no significant improvement in left ventricular function compared with placebo, researchers reported.