Leiden University Medical Center
Expert consensus: Sterile bone inflammation to be called ‘chronic non-bacterial osteitis’
The label “chronic non-bacterial osteitis” should be used to describe sterile bone inflammation in adults, and NSAIDs or cyclooxygenase-2 inhibitors are the recommended first-line treatments, according to a new expert consensus.
Long-term exercise program improves physical function in axial SpA beyond ‘usual care’
A long-term, supervised exercise program for patients with axial spondyloarthritis and severe functional limitations improved functional disability and physical quality of life vs. usual care, according to data published in Rheumatology.
‘Broader and more inclusive design’ needed for novel cancer trials
Individuals with therapy-refractory cancer who received waivers to participate in a clinical trial for off-label targeted therapies achieved similar clinical benefits as those who took part in the study without an exception.
Axial spondyloarthritis can be ‘reliably diagnosed’ shortly after chronic back pain onset
Most patients with recent-onset chronic back pain suspected of axial spondyloarthritis can be “unequivocally and reliably diagnosed” at their first rheumatology visit, according to data published in the Annals of the Rheumatic Diseases.
Patients residing closer to equator develop rheumatoid arthritis earlier
Individuals who live closer to the equator develop rheumatoid arthritis at a younger age, a link that is likely explained by socioeconomic status, according to data published in the Annals of the Rheumatic Diseases.
Prolonged, severe morning stiffness frequent in patients with hand osteoarthritis
Morning stiffness lasting longer than 60 minutes is frequent in patients with hand osteoarthritis, and is linked to greater pain, lower function and decreased quality of life, according to data published in Osteoarthritis and Cartilage.
In older patients with hardened arteries, women at greater risk for CV events vs. men
Among people aged 55 years or older who had a high burden of coronary atherosclerosis, women were at greater risk for a major adverse cardiovascular event than men, researchers reported.
Bimekizumab achieves significant, rapid improvements in axial spondyloarthritis
The use of bimekizumab to inhibit both interleukin-17A and IL-17F was well-tolerated and impactful in improving axial spondyloarthritis outcomes across two phase 3 trials, according to data published in the Annals of the Rheumatic Diseases.
Exercising in the morning could reduce CVD risk
The timing of physical activity could affect the risk for CVD, according to study findings published in the European Journal of Preventive Cardiology.
EULAR/ASAS: Axial SpA management should pursue predefined treatment goal
Axial spondyloarthritis management should be guided by a predetermined treatment target, according to new recommendations published by the Assessment of Spondyloarthritis international Society and EULAR.