Ldl Cholesterol

A novel agent demonstrated a dose-dependent relationship with lectin-like oxidized LDL receptor-1 suppression, a mechanism to lower inflammatory and lipid risk, and was well tolerated in a small study of patients with type 2 diabetes.

A school-based nutrition, gardening and cooking intervention was associated with reductions in LDL and HbA1c in children who participated, researchers reported in JAMA Network Open.

Low-dose statin therapy vs. placebo and six over-the-counter supplements marketed for cholesterol health.

Long-term adherence to PCSK9 inhibition was high among a high-risk cohort with familial hypercholesterolemia, which improved LDL goal attainment when added on top of background statin therapy and ezetimibe, researchers reported.

Low HDL was associated with CHD risk among white adults but not Black adults, and high HDL was not protective of risk in either, researchers reported.

An all-remote hypertension and hypercholesterolemia management program with more than 10,000 participants was associated with significant decreases in BP and LDL at 6 and 12 months compared with education only, researchers reported.

CHICAGO — In adults with atherosclerotic CVD or a risk equivalent, twice-yearly inclisiran injections were associated with a 44% reduction in LDL that was sustained over 4 years with no new safety signals observed, researchers reported.

CHICAGO — Daily rosuvastatin lowered LDL, total cholesterol and serum triglycerides significantly more than placebo and six common over-the-counter dietary supplements, with no supplement lowering LDL more than placebo, researchers reported.

LDL reduction is the major focus in the primary and secondary prevention of atherosclerotic CVD.