Ldl Cholesterol
Daily oral PCSK9 inhibitor cut LDL cholesterol by 50% over 12 weeks
CHICAGO — In a phase 2b study, treatment with a once-daily oral PCSK9 inhibitor added to statin therapy resulted in a more than 50% reduction in LDL cholesterol at 12 weeks in patients with hypercholesterolemia.
Breaking down barriers: How to optimize access, use of PCSK9 inhibitors
Over the years, there have been significant changes to the dyslipidemia medication management guidelines, alongside increasing evidence for novel cholesterol-lowering medications, including PCSK9 inhibitors.
Use of coffee filters in brewing may lower LDL and risk for heart disease
Coffee filters reduce intake of LDL cholesterol-generating compounds found in the brew and subsequently may lower risk for atherosclerotic heart disease, researchers reported.
Novel drug confers weight loss of up to 20% at 1 year in phase 2 study
Maridebart cafraglutide, a novel injectable GLP-1 receptor agonist/GIP receptor antagonist, reduced body weight by up to approximately 20% at 1 year in patients with overweight or obesity without a weight loss plateau, according to a presentation.
Early weight loss with tirzepatide predictive of larger cardiometabolic benefits later on
SAN ANTONIO — Tirzepatide confers significant weight loss and cardiometabolic benefits for patients with diabetes and overweight or obesity, especially for those who lose more weight earlier during treatment, a speaker reported.
VIDEO: Pay attention to CV risk in young adults, measure Lp(a)
BOSTON — In this Healio video exclusive, Erin D. Michos, MD, MHS, FAHA, FACC, FASE, FASPC, discusses her presentation at the Cardiometabolic Health Congress, “Primary Prevention of CVD: The Sooner the Better?”
Top in cardiology: Composite biomarker predicts risk; processed food and heart disease
A single combined measurement of three modifiable biomarkers can predict future cardiovascular events when measured in healthy women at midlife, according to research presented at the European Society of Cardiology Congress.
Measuring three factors can predict women’s 30-year risk for heart disease
A single combined measure of three modifiable biomarkers in healthy women at midlife was predictive of 30-year risk for future cardiovascular events, according to new research presented at the European Society of Cardiology Congress.
Low intake of extra-virgin olive oil within whole-food, plant-based diet may lower LDL
Decreased intake of extra-virgin olive oil within a whole-food, plant-based diet may help to lower LDL among individuals at risk for atherosclerotic CVD, according to a study published in Journal of the American Heart Association.
Eliminating these 14 risk factors may prevent nearly half of dementia cases
PHILADELPHIA — Tackling 14 risk factors for dementia beginning in childhood could prevent or delay nearly half of cases, according to a report from the Lancet Commission presented at the Alzheimer's Association International Conference.