Hypothyroidism

Defining hypothyroidism by thyroid-stimulating hormone level, researchers found the condition was more common in patients with worsening levels of kidney function (as determined by eGFR slope), as well as in those who had proteinuria.

The risk for testing positive for COVID-19 or developing more severe disease does not differ between adults treated for hypothyroidism or hyperthyroidism and euthyroid controls, according to a Danish database analysis.

Three large professional thyroid organizations issued a joint statement calling for new trials of combination therapy to treat hypothyroidism, citing new clinical endpoints and the importance of assessing patient-reported outcomes.

Most adults with free thyroxine levels slightly below the reference range have normal free T4 index values and did not have abnormal findings on pituitary imaging or functional tests, according to a study published in Endocrine Practice.

A majority of adults with hypothyroidism responding to a survey said they were dissatisfied with treatment and reported having a low quality of life score, according to study data published in Clinical Endocrinology.

Children born to mothers diagnosed with thyroid disorders before or during pregnancy were significantly more likely to develop thyroid cancer, with risk persisting into adulthood, according to an analysis of registry data.

A cohort of pregnant women in Canada who were overtreated for hypothyroidism with levothyroxine were more likely to have a preterm delivery than women with normal thyroid-stimulating hormone, according to a study published in Thyroid.

Analysis of more than 3,000 COVID-19-positive adults in New York City showed no association between a history of hypothyroidism and risks for COVID-19 hospitalization, mechanical ventilation or death, according to study data.

Recent study findings showed a higher prevalence of hypothyroidism in patients with Erdheim-Chester disease, a rare blood cancer. It was the top story in endocrinology last week.

Adults with Erdheim-Chester disease, a rare blood cancer, are more likely than those without the disease to have central or primary hypothyroidism and should be screened with a full thyroid panel, according to study findings.