Gout
Weather changes fail to impact risks for osteoarthritis pain, rheumatoid arthritis
Weather changes are not risk factors for rheumatoid arthritis or knee, hip or low back pain, but do appear to influence gout flares, according to a meta-analysis published in Seminars in Arthritis and Rheumatism.
Gout flare severity, recurrence risk not impacted by timing of urate lowering therapy
Starting urate lowering therapy during a gout flare does not impact the flare’s severity, duration or risk for recurrence over the following month, according to a systematic review and meta-analysis.
Biologics fill ‘very unique niches’ in gout management
SCOTTSDALE, Ariz. — Although many rheumatologists may not reach for biologic therapies for gout management, interleukin-1 and 6 inhibitors may have utility in managing mobilization flares, according to a speaker here.
Multiple mechanisms, multiple benefits: SGLT2 inhibition shows promise in lupus, gout
Last November, at the American College of Rheumatology Convergence 2023, several faculty members presented new data on how a class of drugs used in type 2 diabetes may also be beneficial in patients with lupus and gout.
FDA approves Uloric generic for chronic hyperuricemia management in gout
The FDA has approved an abbreviated new drug application for Lupin Limited’s generic febuxostat 40 mg and 80 mg tablets, according to a press release from the manufacturer.
New CLEAR Outcomes data: Bempedoic acid cuts risk for recurrent CV events
A prespecified analysis of the CLEAR Outcomes trial shows that the benefits of bempedoic acid extend to patients with recurrent CV events, including a total reduction in MI risk of 31% vs. placebo.
Patients with ‘pseudogout’ have double the risk for fracture vs controls
SAN DIEGO — Patients with acute calcium pyrophosphate crystal arthritis demonstrate double the risk for fractures vs. matched comparators, according to data presented at ACR Convergence 2023.
Work disability due to inflammatory arthritis greater among lower-paid, manual jobs
People who work lower-paid, manual-labor jobs are more likely to discontinue employment in the first 5 years after an early inflammatory arthritis diagnosis, vs. those who work in managerial or professional capacities, according to data.
‘Gout may not be managed properly’: Premature mortality in gout remains elevated in US, UK
SAN DIEGO — Premature all-cause mortality in gout remains elevated vs. individuals without gout in the United States and United Kingdom, with worse rates reported among women, according to data presented at ACR Convergence 2023.