Genetic Marker
Platelet reactivity score may predict heart attack, stroke risk beyond BP, cholesterol
A platelet reactivity score that identifies people with a hyperreactive platelet phenotype can be used to determine those who might be at elevated risk for a cardiovascular event, researchers reported in Nature Communications.
Lifestyle intervention lowers type 2 diabetes odds for men at high genetic risk
A lifestyle intervention program composed of a healthy diet and increased physical activity can reduce the risk for type 2 diabetes among men with high genetic risk for the disease, according to trial findings.
Q&A: Newly identified genetic loci may allow future prediction of type 2 diabetes risk
A set of newly identified genetic risk factors tied to the development of type 2 diabetes could eventually lead to the discovery of genotypes that allow providers to identify people at highest risk for complications.
Familial SCAD linked to aggregation of common genetic variants
Researchers reported that high concentrations of common genetic variants within families were associated with increased inherited risk for spontaneous coronary artery dissection.
Polygenic risk score incorporating rare variants does not improve fracture prediction
The identification of rare genetic variants that influence bone mineral density did not significantly improve fracture risk screening among a large group of adults, according to data published in Journal of Bone and Mineral Research.
Light or moderate alcohol drinking may not lower risk for type 2 diabetes, obesity
Despite some observational evidence, drinking light or moderate amounts of alcohol may not reduce one’s risk for type 2 diabetes or obesity, according to findings published in The Journal of Clinical Endocrinology & Metabolism.
Navigating incidental genetic findings for CVD requires caution, established framework
Genetic variants associated with CVD found incidentally during testing should be interpreted with caution using a framework that includes a multidisciplinary team of experts, according to a new scientific statement.
REFERCHOL
Assessing odds for subclinical ASCVD by midlife based on maternal inheritance of FH.
ACC joins with World Congress of Cardiology to highlight breaking CV science
The 2023 American College of Cardiology Scientific Session will be held live in New Orleans from Saturday to Monday and virtually, with 43 late-breaking trials and featured clinical research presentations.
Maternal inheritance of FH may increase odds of subclinical coronary calcium by midlife
Researchers in France observed that maternal inheritance of familial hypercholesterolemia was associated with greater odds of having subclinical coronary atherosclerosis compared with paternal inheritance of the gene mutation.