Genetic Background

TV watching in excess of 1 hour per day was associated with increased risk for atherosclerotic heart disease, independent of genetic risk for diabetes, according to new data published in the Journal of the American Heart Association.

Polygenic score is a stronger predictor for thyroid-stimulating hormone levels than free thyroxine and other factors, and could be used to develop individual TSH reference ranges for adults, according to findings published in Thyroid.

Adhering to a diet containing less meat may be beneficial for people with a high genetic risk for obesity, according to data published in Obesity.

PHILADELPHIA — A genetic risk test for patients with multiple sclerosis can identify drugs that may lead to development of progressive multifocal leukoencephalopathy, per data presented at the American Neurological Association annual meeting.

AUSTIN, Texas — Research in genetics as it relates to rheumatologic diseases has a long way to go, but there are steps providers can take to translate current knowledge into actionable patient care, a presenter said.

Daily or near daily aspirin use reduced the risk for nonmucinous ovarian cancer across most strata of genetic risk based on a polygenic score, according to a case-control study published in JAMA Network Open.

The belief among some physicians that patients from underrepresented racial and ethnic groups will have poorer health outcomes because of cultural attitudes or genetics inadvertently reinforces the disparities, according to researchers.

A plant-based diet rich in whole grains, vegetable and legumes was associated with a reduced risk for colorectal cancer in a multiethnic cohort of men but varied by race, ethnicity and site of tumor, according to research in BMC Medicine.

CHICAGO — Environmental chemical exposure is a risk factor for neurodegenerative diseases and neurodevelopmental disorders, an expert at the 2022 American Neurological Association annual meeting said.

CHICAGO — While population and phenotypic diversity are crucial to discovering the root cause of genetic variations that lead to neurodegenerative disease, the answers are not always clear, according to a presenter at ANA 2022.