Exercise

The aorta may be an exercise-responsive plastic organ that remodels in aging competitive endurance athletes, researchers reported in JAMA Cardiology.

Exercise may be more difficult for those with type 2 diabetes and asymptomatic heart failure than those without these conditions due to more epicardial adipose tissue and abnormalities in the structure and function of the left ventricle, according to findings published in the Journal of Diabetes and its Complications.

Individuals with an eating disorder are nearly four times more likely to experience exercise addiction than those without one, according to results of a comparative meta-analysis published in Eating and Weight Disorders.

A small cohort of healthy adolescents with type 1 diabetes showed signs of altered energy metabolism and cardiovascular autonomic regulation after an exercise test compared with peers of similar age and aerobic fitness level, despite exhibiting normal acute cardiometabolic responses, according to findings from a pilot study published in Pediatric Diabetes.

There is now plentiful evidence that medical therapy benefits patients with peripheral artery disease, which is reflected in guidelines but not followed nearly enough, a speaker stated at the International Symposium on Endovascular Therapy.

The roles of diabetes educators — and the settings where they work — are evolving to address the increasing prevalence of diabetes and meet new demands for population-level diabetes performance measures. To signal this evolution, the American Association of Diabetes Educators is promoting a new name for these professionals: diabetes care and education specialists.

Low-carb, ketogenic, Mediterranean, time-restricted, alternate-day fasting — Healio readers were interested in the effects of different eating plans on weight loss and cardiometabolic measures. Also, different exercise programs may benefit different people, but it’s never too late to start.

In a cohort of Finnish men, those who went cross-country skiing more frequently and for longer duration had reduced risk for type 2 diabetes vs. those who did not participate in the sport, according to findings published in Diabetes/Metabolism Research and Reviews.

Boehringer Ingelheim and Eli Lilly and Co. announced negative top-line results for its EMPERIAL-Reduced and EMPERIAL-Preserved trials, nothing that the SGLT2 inhibitor empagliflozin did not meet the primary endpoint of improvements in exercise ability according to the 6-minute walk test from baseline to 12 weeks compared with placebo in patients with chronic HF with reduced and preserved ejection fraction.

News that the FDA is investigating metformin products to determine if potentially carcinogenic agents are present was one of the week’s top stories in endocrinology.