Cognitive Impairment
Degree of cognitive impairment after 6 months dependent on TBI severity
In a cohort of adults with traumatic brain injury, level of impairment for those who exhibited cognitive impairment after 6 months was directly correlated to TBI severity, according to research from JAMA Network Open.
FDA grants breakthrough device designation to digital therapeutic for schizophrenia
The FDA has granted breakthrough device designation for CT-155, an investigational prescription digital therapeutic co-developed by Click Therapeutics and Boehringer Ingelheim to treat negative symptoms of schizophrenia.
Small HDL particles in brain appear protective against Alzheimer’s disease
Small HDL particles play a significant role in the prevention of Alzheimer’s disease, and an inherited gene present in one in four people hinders its production in the brain, increasing risk for cognitive decline, a speaker reported.
Food insecurity associated with dementia risk
Food insecurity was linked to an increased risk for dementia and faster memory decline among older adults, according to a study published in JAMA Network Open.
MRIs reveal brain microstructure changes in people with long COVID
A novel MRI technique showed brain microstructure changes in people who have had COVID-19, and it traced long COVID symptoms to specific networks of the brain, according to a study.
Intervention for uncontrolled hypertension also lowers dementia risk
PHILADELPHIA — A 48-month intervention to lower BP in patients with uncontrolled hypertension also reduced risk for dementia and cognitive impairment, according to data presented at the American Heart Association Scientific Sessions.
Machine learning model most accurately predicts levels of cognitive impairment
An artificial intelligence-based machine learning model that diagnosed cognitive impairment in Alzheimer’s disease extracted information more accurately than standard screening or human analysis, according to a poster presentation at CTAD.
Eye-tracking AI device aids in detection of dementia risk in underrepresented group
A novel, eye-tracking metrics device aided in the detection of dementia risk in a small population of Colombian individuals with differing levels of education, according to a poster presented at CTAD.
FDA grants orphan drug designation to oral Huntington’s disease therapy
The FDA has granted orphan drug designation to an investigational oral therapeutic for the treatment of Huntington’s disease, according to the manufacturer.
High baseline systolic blood pressure may be risk factor for dementia cognitive impairment
Higher baseline systolic blood pressure may be a strong risk factor for dementia and cognitive impairment in patients with chronic kidney disease, according to a recently published study. “High blood pressure and cognitive impairment are common in adults with chronic kidney disease,” Seda Babroudi, MD, of the William B. Schwartz Division of Nephrology in Boston, and colleagues wrote.