Cholesterol

Data show that higher cumulative remnant cholesterol and greater remnant cholesterol variability are each associated with elevated risk for atherosclerosis, independent of LDL, triglycerides level and other traditional CV risk factors.

Postmenopausal women with high total or HDL cholesterol have an increased risk for heart failure compared with women with normal cholesterol levels, according to a study published in Menopause.

An analysis of nearly 500 million cholesterol readings globally shows LDL levels vary widely by country and region even after adjusting for age and sex, suggesting population-specific interventions may be needed, researchers reported.

Nearly one-quarter of adults with documented thyroid nodules also have diabetes, according to a study published in the Journal of Clinical Medicine Research.

Adults with obesity who used semaglutide for weight loss reduced their 10-year risk for atherosclerotic cardiovascular disease, according to findings presented at the European Congress on Obesity.

Adults with overweight or obesity receiving semaglutide lost 13.4% of their body weight at 1 year, according to findings from a real-world study presented at the European Congress on Obesity.

This installment of Pipeline Pulse focuses on a single cardiovascular risk factor, lipoprotein(a), and examines two CV outcomes trials aimed at reducing CV events through Lp(a) reduction.

About 75% of adults with heterozygous familial hypercholesterolemia do not meet guideline-recommended LDL treatment targets, whereas women with familial hypercholesterolemia are less likely than men to be appropriately treated, data show.

The NIH announced a trial it is funding has been stopped early because an interim analysis found daily statin use greatly prevented major adverse CV events in people living with HIV.