Celiac Disease
Limbal stem cell deficiency seen in celiac disease variant
Celiac disease is an autoimmune condition that usually presents with intestinal disorders. Ophthalmic manifestations, though, have been noted, and bilateral limbal stem cell deficiency is rarely reported in celiac disease. The ocular manifestations involve retinopathy, cataract, vitamin A deficiency, and pseudotumor cerebri and its related presentations. Here, we report two siblings with ocular features suggestive of limbal stem cell deficiency and dermatological manifestations that led to the detection of celiac gene defect positivity.
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Latest evidence that celiac disease runs in families prompts Mayo Clinic doctors to call for more screening
A “high prevalence” of celiac disease was found among screened first-degree relatives of patients with the condition, according to findings recently published in Mayo Clinic Proceedings. The findings prompted researchers to encourage all parents, children and siblings of patients with celiac disease to be screened for the disorder.