Bleeding

CHARLOTTE, N.C. — Endoscopic therapy yielded lower rates of rebleeding, mortality and surgery compared with conservative therapy in patients with bleeding peptic ulcer diseases, according to a presenter at ACG Annual Scientific Meeting.

CHARLOTTE, N.C. — Prophylactic endotracheal intubation prior to endoscopy was not beneficial for patients with upper gastrointestinal bleeding and was instead tied to adverse risks, researchers reported at ACG 2022 Annual Scientific Meeting.

For adults who undergo PCI with a drug-eluting stent, recommendations for dual antiplatelet therapy have evolved from a standard 1-year duration for most patients to a more nuanced approach that balances risks for ischemia and bleeding.

The FDA granted clearance to Medtronic’s endoscopic hemostasis system, Nexpowder, intended to improve visibility and management of upper gastrointestinal bleeding not linked to varices, according to a company press release.

Long-term P2Y12 inhibition after PCI reduced bleeding at 3 years compared with dual antiplatelet therapy, with no significant differences observed for ischemic events, according to new data from the SMART-CHOICE trial.

BOSTON — Ultrasound-guided femoral access improved first attempt success in coronary procedures but did not reduce the occurrence of major bleeding and vascular complications vs. fluoroscopy alone, a speaker reported.

Two-thirds of women of child-bearing age who began taking anticoagulants for acute venous thromboembolism had abnormally heavy menstrual bleeding in the months that followed therapy initiation, according to data from a prospective study.

Asundexian on top of dual antiplatelet therapy successfully reduced factor XIa activity after acute MI and stroke with no excess bleeding risk, two speakers reported.

In a meta-analysis of seven trials of patients who had coronary angiography with or without PCI, those who had transradial access had lower 30-day rates of mortality and major bleeding compared with those who had transfemoral access.

In adults with high bleeding risk, early deintensification of dual antiplatelet therapy after PCI was associated with less bleeding and no increased ischemic risk beyond 12 months vs. standard treatment, according to a speaker.