Bisphosphonate

Older adults who sustain a hip fracture after discontinuing risedronate following at least 5 years of treatment adherence have a higher post-fracture mortality risk than those who continue using risedronate, according to study data.

The FDA has added a boxed warning for denosumab to advise patients with advanced chronic kidney disease of an increased risk for severe hypocalcemia, according to an FDA drug safety communication.

SANTA FE, N.M. — In this video exclusive, Michael R. McClung, MD, discusses strategies for drug holidays and transitions between osteoporosis therapies.

Antiresorptive medications such as oral bisphosphonates have a minimal effect on change in lumbar spine trabecular bone score among older adults, according to a study published in The Journal of Bone and Mineral Research.

LAS VEGAS — Use of bisphosphonates prior to primary total hip arthroplasty may be an independent risk factor for periprosthetic fracture among patients with osteoporosis, according to results presented here.

In an update to its guidance on primary osteoporosis, ACP recommended bisphosphonates as a first line of defense to reduce fracture risk in men and postmenopausal women.

A new clinical practice guideline from the Endocrine Society recommends treatment with IV bisphosphonates or denosumab in addition to adequate hydration for adults with moderate hypercalcemia of malignancy.

Among South-East Asian adults, bisphosphonate use in is not associated with differences in clinical outcomes or mortality after an atypical femur fracture, according to study data published in Bone.

What does the PAPA spectrum disorder teach us about SAPHO? Is SAPHO an autoinflammatory condition or part of the SpA spectrum? Why have antibiotics been used to treat this condition? Find out in this episode!

In a cohort of women, NSAID use significantly decreased the efficacy of the bisphosphonate clodronate for preventing bone loss and fractures, according to findings from a post hoc analysis.