Biopsy

LONDON — Ozempic improved cardiometabolic parameters and markers of liver injury yet failed to improve liver fibrosis in patients with nonalcoholic steatohepatitis and compensated cirrhosis, according to late-breaker data presented here.

SAN DIEGO — Although percutaneous liver biopsy is still the “gold standard,” advances in techniques and increased use of endoscopic ultrasound-guided biopsy may soon change that dynamic, according to a debate at Digestive Disease Week 2022.

Biopsy details, including the operator’s training and any intra-articular steroids used prior to the procedure, should be reported in every study involving synovial tissue, according to new EULAR points to consider.

Vibration-controlled transient elastography and fibrosis-4 index are effective alternatives to liver biopsy when evaluating risk for liver-related events in patients with nonalcoholic fatty liver disease, according to study results.

The presence of advanced tertiary lymphoid tissues in protocol biopsies correlated with decline in graft function among kidney transplant recipients, according to data published in the Journal of the American Society of Nephrology.

Vascular ultrasound, using high-end equipment and optimized settings, may be an effective replacement for temporal artery biopsy as a first-line diagnostic tool in patients with suspected giant cell arteritis, according to a Danish study.

C. Jonathan D. Foster, DO, FACOI, spoke with Healio about the utility of repeat Helicobacter pylori biopsies in patients with previously negative tests.

Aldafermin did not reach statistical significance on dose-dependent improvement in fibrosis on liver biopsy in patients with nonalcoholic steatohepatitis, according to a presentation at The Liver Meeting Digital Experience.

Lower baseline eGFR, use of proton pump inhibitors and extrarenal immune-related adverse events are independent risk factors for AKI in patients treated with immune checkpoint inhibitors, according to data presented at ASN Kidney Week.

When asked how the decision to perform a kidney biopsy was determined, nephrologists responded with substantial variability. According to data published in Kidney Medicine, several factors go into the decision.