Atherosclerotic Cardiovascular Disease

An LPA genetic risk score with 43 single nucleotide variants provided similar risk prediction for atherosclerotic CVD compared with measuring lipoprotein(a), researchers found.

Over 2 decades, various research and analyses have indicated that although residual LDL and inflammation are both associated with CV risk, they should be targeted individually for optimal outcomes in secondary prevention, a speaker said.

Alerting cardiologists with active or passive prompts within electronic health records regarding statin therapy in eligible patients with atherosclerotic CVD did not significantly change prescribing rates, researchers found.

Adverse pregnancy outcomes, particularly hypertensive disorders of pregnancy and low birth weight, were independently linked to atherosclerotic CVD in postmenopausal women, researchers found.

Among patients with type 2 diabetes and atherosclerotic CVD, the SGLT2 inhibitor ertugliflozin reduced risk for first and total HF events compared with placebo, according to new data from the VERTIS CV study.

The current literature does not support the use of aspirin for primary prevention in patients with diabetes, and physicians must balance the benefits of prevention with the increased risk for major bleeding, according to a speaker.

Coronary artery calcium scoring can be used as a decision aid, although more trials are needed for guidelines to endorse its use as a class IA recommendation, according to a presentation at Society of Cardiovascular Computed Tomography Annual Scientific Meeting.

Statin initiation in older U.S. veterans free from atherosclerotic CVD at baseline reduced the risk for CV and all-cause mortality, researchers found in a retrospective cohort study.

Incorporating a question about physical activity with coronary artery calcium scoring improved prediction of clinical and mortality risk in older patients, researchers reported.

Six primary prevention risk assessment scores, including the Framingham risk score, Atherosclerotic Cardiovascular Disease risk score and Adult Treatment Panel III risk score, did not adequately predict the rates of CVD in women with ischemia and no obstructive CAD, according to a study published in the Journal of the American Heart Association.