Antihistamines

Solutions for halting osteoarthritis progression and avoiding need for joint replacement remain elusive, but new therapy options, including a novel injection, made headlines in 2022.

In this edition, neurologic effects of COVID-19 among pediatric populations, FDA accepts NDA for extended-release carbidopa/levodopa, antihistamines could be promising therapy for Parkinson’s disease and more.

LOUISVILLE, Ky. — Patients with chronic spontaneous urticaria experienced improvements with dupilumab, according to a study presented at the American College of Asthma & Immunology Annual Scientific Meeting.

CHICAGO — A literature-based discovery machine learning algorithm suggested that antihistamines could be adjuvants to levodopa for Parkinson’s disease, a poster showed at the 2022 American Neurological Association annual meeting.

Antihistamines proved to be efficacious as adjunct therapy in the treatment of alopecia areata, whereas antihistamines as monotherapy and dupilumab warrant further research, according to a study.

As drug overdose deaths grab headlines in the U.S., 14.7% of these deaths were positive for antihistamines and 3.6% of them were classified as antihistamine-involved, according to data published in Morbidity and Mortality Weekly Report.

The nasal spray GSP301 effectively treated symptoms of seasonal allergic rhinitis in children aged 6 to 11 years with a positive impact on their quality of life, according to a study published in Annals of Allergy, Asthma & Immunology.

Fever, angioedema, joint involvement and gastrointestinal symptoms were among the factors that predicted ED and urgent care reutilization among children with amoxicillin-associated reactions, according to study results.

Intranasal corticosteroid and intranasal antihistamine therapies did a better job of alleviating nasal and ocular symptoms in allergic rhinitis than intranasal corticosteroid therapy alone, according to a review.

The use of H1 or H2 antihistamines may mitigate some side effects of peanut oral immunotherapy, but they did not influence quality of life, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.