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December 29, 2022
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Antihistamines may slow knee osteoarthritis progression, novel injection shows promise

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Solutions for halting osteoarthritis progression and avoiding need for joint replacement remain elusive, but new therapy options, including a novel injection, made headlines in 2022.

Check out a few of the top stories from Healio’s 2022 coverage of osteoarthritis below:

KneeInflammation

Solutions for halting osteoarthritis progression and avoiding need for joint replacement remain elusive, but new therapy options, including a novel injection, made headlines in 2022. Source: Adobe Stock

Patients using antihistamines show decreased structural progression in knee osteoarthritis

Patients with knee osteoarthritis receiving antihistamines demonstrate less structural disease progression, compared with those who did not take antihistamines, over 2 years, according to data presented at the EULAR 2022 Congress. Read more.

TPX-100 injection may ‘reduce or eliminate’ need for knee replacement in osteoarthritis

TPX-100, a novel intra-articular injection, yielded strong improvements in bone shape change and function that may ultimately minimize the need for knee replacement, according to a speaker at the 2022 OARSI World Congress. Read more.

Choice of osteoporosis drug sequence has ‘important clinical consequences’

Understanding when to switch from one class of drugs to another is critical to maintaining bone health and preventing fractures in osteoporosis, according to data presented at the Congress of Clinical Rheumatology East. Read more.

Walking, maximum-level activity reduce odds of cartilage loss in knee osteoarthritis

Increasing rates of walking, standing or maximum-level activity is associated with reductions in cartilage loss in knee osteoarthritis, according to a speaker at the 2022 OARSI World Congress. Read more.

Data find ‘direct correlation’ between air pollution and osteoporosis, autoimmune disease

There is a “direct correlation” between microscopic particles found in air pollution and increased incidence of osteoporosis and autoimmune disease in a cohort of individuals in Italy, according to a presenter at the EULAR 2022 Congress. Read more.