Antibodies
Anti-drug antibodies linked with TNF inhibitor treatment failure in noninfectious uveitis
Higher anti-drug antibody levels were associated with an increased risk for tumor necrosis factor inhibitor treatment failure in patients with noninfectious uveitis who received adalimumab, according to a study.
Breakthrough COVID infection in patients with lymphoma may be due to lost vaccine efficacy
VIDEO: Antibodies can provide useful insights into neuropathy
CHICAGO — Divyanshu Dubey, MBBS, discusses the use of antibody evaluations in the workup for neuropathies during a presentation at the 2022 American Neurological Association’s annual meeting.
Early data show Pfizer’s omicron booster ‘substantially’ boosted antibodies against BA.5
Early data from trials assessing the new Pfizer and BioNTech omicron-adapted booster vaccine show that the vaccine substantially increased protective antibodies against the BA.5 subvariant in adults.
High-dose trivalent inactivated influenza vaccine worked well in patients on hemodialysis
Patients on hemodialysis who received the high-dose trivalent inactivated influenza vaccine showed a stronger seroresponse than those who received other vaccines, according to data published the American Journal of Kidney Diseases.
Memo Therapeutics examines treatment for BK polyomavirus in kidney transplant recipients
Data show most pregnant women with COVID-19 pass antibodies to neonates
LISBON, Portugal — Pregnant women with SARS-CoV-2 infection passed antibodies to newborns in most cases, although there were no cases of neonatal infection in a study presented here.
Adherence-promotion strategies correlate with reduced allograft rejection
Implementation of evidence-based adherence-promotion strategies correlated with a 50% reduction in acute allograft rejection for 2 years among kidney transplant recipients.
Low incidence of donor-specific antibodies for kidney transplant recipients with COVID-19
Despite a significant decrease in immunosuppression, the occurrence of post-COVID-19 donor-specific antibodies among COVID-19-positive kidney transplant recipients was low, according to data published in Kidney International Reports.
Bamlanivimab for COVID-19 may harm patients with endogenous neutralizing antibodies
The monoclonal antibody bamlanivimab may be effective in treating hospitalized patients with SARS-CoV-2 infection if they have no detectable levels of endogenous neutralizing antibodies prior to administration, according to researchers.