Oncology News

A trial investigating mirvetuximab soravtansine monotherapy in certain patients with platinum-sensitive ovarian cancer met its primary endpoint of improved objective response rate, according to the agent’s manufacturer.

BOSTON — Tumor samples from Black women diagnosed with triple-negative breast cancer expressed higher levels of insulin signaling than samples from white women, suggesting hyperinsulinemia may play a role in disease outcomes, data show.

BOSTON — Breast cancer survivors are more likely to have weight gain of 10% or more during follow-up compared with healthy controls, with the strongest predictors younger age at diagnosis and lower weight at baseline, data show.

CHICAGO — Trastuzumab deruxtecan extended PFS compared with standard chemotherapy for certain patients with pretreated breast cancer, according to findings presented at ASCO Annual Meeting.

A study assessing the efficacy of pembrolizumab met a key secondary endpoint of extending OS, in combination with chemotherapy, among patients with high-risk early-stage triple-negative breast cancer, according to the agent’s manufacturer.

CHICAGO — Cancer risk among women varied based on the type of menopausal hormone therapy they used, according to randomized study results scheduled for presentation at ASCO Annual Meeting.

Men vaccinated for HPV less frequently developed all related cancers, particularly head and neck cancers, according to findings scheduled for presentation at ASCO Annual Meeting.

CHICAGO — The majority of young breast cancer survivors who attempted pregnancy became pregnant, according to prospective study results scheduled for presentation at ASCO Annual Meeting.

In France, HPV vaccination at school significantly increased vaccination coverage among adolescents aged 11 to 14 years, according to study results published in JAMA Network Open.

A 5-year interval between cervical cancer screenings using HPV testing does not increase risk for cervical precancer detection compared with cytology every 3 years and may be a more effective screening method long term, researchers report.