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Pulmonary Vascular Disease News
FDA clears investigational new drug application for lorundrostat in OSA, hypertension
The FDA approved the phase 2 Explore-OSA trial set to assess the highly selective aldosterone synthase inhibitor, lorundrostat, in adults with obstructive sleep apnea and hypertension, according to a press release.
Q&A: Trial to investigate PAH monotherapy vs. dual therapy in pediatric patients
There has been little research on optimal treatments for pediatric patients with pulmonary arterial hypertension, but the Kids MoD PAH Trial is expected to change this by clearing up if sildenafil plus bosentan or sildenafil only is better.
Misdiagnosis of heart failure possible in patients with COPD
PHILADELPHIA — Heart failure with preserved ejection fraction may be misdiagnosed in patients with COPD due to symptoms/signs being misinterpreted as COPD, according to a presentation at the 2024 GOLD COPD International Conference.
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Awareness of pulmonary hypertension in patients with COPD growing
PHILADELPHIA — With the 2025 GOLD report newly featuring a section dedicated to pulmonary hypertension, it is important that clinicians expand their knowledge of this comorbidity, according to a presentation.
Topline results: Winrevair lowers risk for mortality in patients with advanced PAH
Adults with pulmonary arterial hypertension functional class three or four faced a decreased risk for all-cause mortality or morbidity events with Winrevair vs. placebo, according to phase 3 ZENITH trial topline results.
2025 GOLD report addresses cardiovascular risk, climate change, pulmonary hypertension
PHILADELPHIA — To reflect developments in COPD research and care, the 2025 Global Initiative for Chronic Obstructive Lung Disease report features three new sections and several sections that have been updated/revised.
Deep learning model outperforms echocardiography in identifying pulmonary hypertension
BOSTON — A multimodal fusion model outperformed transthoracic echocardiography in identifying pulmonary hypertension, according to a study presented at the CHEST Annual Meeting.
Fewer deaths in pulmonary embolism plus pancreatic cancer cases in 2020 vs. 2001
BOSTON — Fewer patients hospitalized for acute pulmonary embolism with pancreatic cancer died in 2020 compared with rates in 2001, according to a presentation at the CHEST Annual Meeting.
In-hospital mortality elevated in cystic fibrosis cardiac hospitalizations
BOSTON — Hospitalization for a cardiac cause vs. a noncardiac cause in patients with cystic fibrosis yielded elevated in-hospital mortality, according to a presentation at the CHEST Annual Meeting.
Treatment in PAH similar with, without mental health comorbidities
BOSTON — Having pulmonary arterial hypertension plus a mental health comorbidity did not result in differing treatments or outcomes from those without this comorbidity, according to data presented at the CHEST Annual Meeting.
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Headline News
Medicare selects 15 drugs for second round of price negotiations, including semaglutide
January 17, 20252 min read -
Headline News
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January 17, 20253 min read -
Headline News
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