January 18, 2012
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Study: ADHD medications not associated with serious cardiovascular risk

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Patients who take medications for attention-deficit/hyperactivity disorder faced no increased cardiovascular risks, according to a retrospective population-based cohort study.

Researchers analyzed records of more than 440,000 young and middle-aged adult subjects, including more than 150,000 who used ADHD medications from 1986 to 2005.

For current use vs. nonuse of ADHD medications, the ratio of serious cardiovascular events was 0.83 (95% CI, 0.72-0.96).

“We found no evidence of an increased risk of [myocardial infarction], [sudden cardiac death] or stroke associated with current use compared with nonuse or remote use of ADHD medications,” the authors wrote.

Disclosure: Research funded in part by Vanderbilt, Harvard Pilgrim Health Care Institute, the Agency for Healthcare Research and Quality, US Department of Health and Human Services. Project also funded by the FDA under contracts with Kaiser Permanente Northern California, Vanderbilt, Ingenix and Harvard Pilgrim Health Care Institute. Project also funded by the National Institute on Aging.