HIV/AIDS News

Infants who received six-week extended nevirapine prophylaxis to prevent HIV transmission had a higher frequency of resistant virus at 6 months of age, according to data presented at the 17th Conference on Retroviruses and Opportunistic Infections in San Francisco.

Supplementing extended nevirapine prophylaxis with zidovudine significantly reduced the risk of nevirapine resistance at 14 weeks in infants who contracted HIV in utero, provided that the prophylaxis was stopped by 6 weeks of age, according to results from the Post-Exposure Prophylaxis of Infants-Malawi trial.

Once-daily elvitegravir — when added to a protease inhibitor-based background regimen — may be as effective and tolerable in adolescents as it is in adults, according to findings presented at the 17th Conference on Retroviruses and Opportunistic Infections, held in San Francisco.

Two formulations of the vaginal microbicide gel PRO2000 failed to demonstrate efficacy against transmission of HIV, according to study findings.

Mothers who receive single-dose nevirapine may be at higher risk for passing on resistant HIV virus to their breast-feeding infant, according to data presented at the 17th Conference on Retroviruses and Opportunistic Infections in San Francisco.

New HIV infections in children aged 2 to 14 years may have decreased by more than 50% in South Africa between 2002 and 2008, according to findings presented at the 17th Conference on Retroviruses and Opportunistic Infections, held in San Francisco.

Slow movement on prevention interventions and an increasing number of prophylaxis failures have contributed to the 2 million children who are infected with HIV worldwide, according to findings presented at the 17th Conference on Retroviruses and Opportunistic Infections, held in San Francisco.

Differences in rates of perinatal HIV infection between races/ethnicities in the United States have persisted over the past several years, with 69% of cases per year occurring in black patients, 16% in Hispanic patients and 11% in white patients, according to a recent study.

A reduction in the normal duration of breast-feeding by mothers with HIV to uninfected children may be associated with increased child mortality extending into the second year of life, according to new results from a study conducted in Zambia.